Sewell holds the American League record (20) for the most active years as a catcher. He caught for the Cleveland Indians, Washington Senators and Chicago White Sox. Sewell managed the St. Louis Browns from 1941 to 1944, the only season the Browns won the American League pennant. He was Sporting News Manager of the Year in 1944. In addition, Sewell managed the Cincinnati Redlegs from 1950 to 1952.